Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Efficient Preparation and Bioactivity Evaluation of Glycan-Defined Glycoproteins.

ACS chemical biology - 15 Oct 2021

Hyun Ji Young, Kim Sanggil, Lee Chang-Hee, Lee Hyun Soo, Shin Injae

Abstract excerpt

Owing to the generation of heterogeneous glycoproteins in cells, it is highly difficult to study glycoprotein-mediated biological events and to develop biomedical agents. Thus, general and efficient methods to prepare homogeneous glycoproteins are in high demand. Herein, we report a general method for the efficient preparation of homogeneous glycoproteins that utilizes a combination of genetic code expansion and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biocatalysis
Share to Alkynes
Share to Azides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to beta-N-Acetylhexosaminidases

Share to G(M2) Ganglioside

Share to Lectins

Share to Polysaccharides

Share to THP-1 Cells

Source

Identifiers

PMID: 33232137
DOI: 10.1021/acschembio.0c00629

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Efficient Preparation and Bioactivity Evaluation of Glycan-Defined Glycoproteins.PMID 33232137Read ↗

Glycosyltransferases as versatile tools to study the biology of glycansSemantic proximity Read ↗

A Chemoenzymatic Strategy for Site-Specific Glyco-Tagging of Native Proteins for the Development of BiologicalsSemantic proximity Read ↗

Review of Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols : A book edited by Alain BeckSemantic proximity Read ↗

Multi-Tag: A modular platform of bioorthogonal probes for multi-modal (glyco)protein analysisSemantic proximity Read ↗

Glycosylation Shapes the Efficacy and Safety of Diverse Protein, Gene and Cell TherapiesSemantic proximity Read ↗

Glycosylation shapes the efficacy and safety of diverse protein, gene and cell therapiesSemantic proximity Read ↗

Metabolic precision labeling enables selective probing of O-linked <i>N</i> -acetylgalactosamine glycosylationSemantic proximity Read ↗

Protein-Targeted Glycan Editing on Living Cells Disrupts KRAS Signaling.Semantic proximity Read ↗

Strategies and Tactics for the Development of Selective Glycan-Binding ProteinsSemantic proximity Read ↗

Bioconjugation using mutant glycosyltransferases for the site-specific labeling of biomolecules with sugars carrying chemical handles.Semantic proximity Read ↗

Multiplexed engineering glycosyltransferase genes in CHO cells via targeted integration for producing antibodies with diverse complex-type N-glycansSemantic proximity Read ↗

Click Lipid Nanoparticles for the Delivery of mRNA to Metabolically Labeled Cancer CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.