Article
Potential anti-EBV effects associated with elevated interleukin-21 levels: a case report.
BMC infectious diseases - 23 Nov 2020
Assing Kristian, Nielsen Christian, Jakobsen Marianne, Andersen Charlotte B, Skogstrand Kristin, Gaini Shahin, Preiss Birgitte, Mortensen Sussi Bagge, Skov Marianne Nielsine, Rasmussen Line Dahlerup
Abstract excerpt
BACKGROUND: Germinal center derived memory B cells and plasma cells constitute, in health and during EBV reactivation, the largest functional EBV reservoir. Hence, by reducing germinal center derived formation of memory B cells and plasma cells, EBV loads may be reduced. Animal and in-vitro models have shown that IL-21 can support memory B and plasma cell formation and thereby potentially contribute to EBV...
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