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Article

TAO-kinase 3 governs the terminal differentiation of NOTCH2-dependent splenic conventional dendritic cells.

Proceedings of the National Academy of Sciences of the United States of America - 8 Dec 2020

Vanderkerken Matthias, Maes Bastiaan, Vandersarren Lana, Toussaint Wendy, Deswarte Kim, Vanheerswynghels Manon, Pouliot Philippe, Martens Liesbet, Van Gassen Sofie, Arthur Connie M, Kirkling Margaret E, Reizis Boris, Conrad Daniel, Stowell Sean, Hammad Hamida, Lambrecht Bart N

Abstract excerpt

Antigen-presenting conventional dendritic cells (cDCs) are broadly divided into type 1 and type 2 subsets that further adapt their phenotype and function to perform specialized tasks in the immune system. The precise signals controlling tissue-specific adaptation and differentiation of cDCs are currently poorly understood. We found that mice deficient in the Ste20 kinase Thousand and One Kinase 3 (TAOK3) lacked...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33214146
DOI: 10.1073/pnas.2009847117
PMCID: PMC7733863

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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