Article
Distinct gene expression patterns correlate with developmental and functional traits of iNKT subsets.
Nature communications - 10 Oct 2016
Georgiev Hristo, Ravens Inga, Benarafa Charaf, Förster Reinhold, Bernhardt Günter
Abstract excerpt
Invariant natural killer T (iNKT) cells comprise a subpopulation of innate lymphocytes developing in thymus. A new model proposes subdividing murine iNKT cells into iNKT1, 2 and 17 cells. Here, we use transcriptome analyses of iNKT1, 2 and 17 subsets isolated from BALB/c and C57BL/6 thymi to identify candidate genes that may affect iNKT cell development, migration or function. We show that Fcɛr1γ is involved in...
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