Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Myeloid Krüppel-like factor 2 is a critical regulator of metabolic inflammation

18 Nov 2020

Abstract excerpt

Substantial evidence implicates crosstalk between metabolic tissues and the immune system in the inception and progression of obesity. However, molecular regulators that orchestrate metaflammation both centrally and peripherally remains incompletely understood. Here, we identify myeloid Krüppel-like factor 2 (KLF2) as an essential regulator of obesity and its sequelae. In mice and humans, consumption of a fatty...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Kruppel-like factors research
Share to Peroxisome Proliferator-Activated Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33208733
DOI: 10.1038/s41467-020-19760-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Myeloid Krüppel-like factor 2 is a critical regulator of metabolic inflammationPMID 33208733Read ↗

BMAL2 controls adipose tissue inflammation and metabolic adaptation during obesitySemantic proximity Read ↗

Four-and-a-half LIM domain protein 2 (FHL2) deficiency protects mice from diet-induced obesity and high FHL2 expression marks human obesity.Semantic proximity Read ↗

The transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis.Semantic proximity Read ↗

Krüppel-like factor 4 regulates macrophage polarizationSemantic proximity Read ↗

KLF10 Deficiency in CD4+ T Cells Triggers Obesity, Insulin Resistance, and Fatty Liver.Semantic proximity Read ↗

Role of the mixed-lineage protein kinase pathway in the metabolic stress response to obesity.Semantic proximity Read ↗

<i>Tlr2</i> is critical for diet‐induced metabolic syndrome in a murine modelSemantic proximity Read ↗

BNIP3-mediated mitophagy in macrophages regulates obesity-induced adipose tissue metaflammationSemantic proximity Read ↗

Obesity activates toll-like receptor-mediated proinflammatory signaling cascades in the adipose tissue of mice.Semantic proximity Read ↗

Kruppel-Like Factor 2 Is a Transcriptional Regulator of Chronic and Acute InflammationSemantic proximity Read ↗

Myeloid Krüppel-like factor 4 deficiency augments atherogenesis in ApoE-/- mice--brief report.Semantic proximity Read ↗

ZFP90 Serves as a Transcriptional Brake on NF-kB Signaling to Attenuate Diet-Induced MASLD ProgressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.