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Article

The transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis.

Nature communications - 28 Jul 2016

Coppo Maddalena, Chinenov Yurii, Sacta Maria A, Rogatsky Inez

Abstract excerpt

Diet-induced obesity causes chronic macrophage-driven inflammation in white adipose tissue (WAT) leading to insulin resistance. WAT macrophages, however, differ in their origin, gene expression and activities: unlike infiltrating monocyte-derived inflammatory macrophages, WAT-resident macrophages counteract inflammation and insulin resistance, yet, the mechanisms underlying their transcriptional programming...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27464507
DOI: 10.1038/ncomms12254
PMCID: PMC4974480

Genes

GRIP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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