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Genetic Determinants of Antibody-Mediated Immune Responses to Infectious Diseases Agents: A Genome-Wide and HLA Association Study

24 Sept 2020

Abstract excerpt

BACKGROUND: Infectious diseases are causally related to a large array of noncommunicable diseases (NCDs). Identifying genetic determinants of infections and antibody-mediated immune responses may shed light on this relationship and provide therapeutic targets for drug and vaccine development. METHODS: We used the UK biobank cohort of up to 10 000 serological measurements of infectious diseases and genome-wide...

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PMID: 33204752
DOI: 10.1093/ofid/ofaa450

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