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Human genomics of the humoral immune response against polyomaviruses

9 Jun 2021

Abstract excerpt

Abstract Human polyomaviruses are widespread in humans and can cause severe disease in immunocompromised individuals. To identify human genetic determinants of the humoral immune response against polyomaviruses, we performed genome-wide association studies and meta-analyses of qualitative and quantitative immunoglobulin G responses against BK polyomavirus (BKPyV), JC polyomavirus (JCPyV), Merkel cellpolyomavirus...

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PMID: 34532061
DOI: 10.1093/ve/veab058

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