Article

A frequent ancestral NFKB1 variant predicts risk of infection or allergy

2022-11-24

Abstract excerpt

Infectious agents contribute significantly to the global burden of diseases, through both acute infection and their chronic sequelae. We leveraged the UK Biobank to identify genetic loci that influence humoral immune response to multiple infections. From 45 genome-wide association studies in 9,611 participants from UK Biobank, we identified NFKB1 as a locus associated with quantitative antibody responses to multip...

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Literature Corpus work: 8e3c6ff5-fed3-5e9f-acdf-afab4dc74c1c
DOI: 10.1101/2022.11.24.22282707

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