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HER2/PI3K/AKT pathway in HER2-positive breast cancer: A review

14 Jun 2024

Abstract excerpt

Breast cancer is currently the most commonly occurring cancer globally. Among breast cancer cases, the human epidermal growth factor receptor 2 (HER2)-positive breast cancer accounts for 15% to 20% and is a crucial focus in the treatment of breast cancer. Common HER2-targeted drugs approved for treating early and/or advanced breast cancer include trastuzumab and pertuzumab, which effectively improve patient...

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PMID: 38875362
DOI: 10.1097/md.0000000000038508

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