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Article

A Comprehensive Review of HER2 in Cancer Biology and Therapeutics

2024-06-07

Abstract excerpt

Human epidermal growth factor receptor 2 (HER2), a targetable transmembrane glycoprotein receptor of the epidermal growth factor receptor (EGFR) family, plays a crucial role in cell proliferation, survival, and differentiation. Aberrant HER2 signaling is implicated in various cancers, particularly breast and Gastric cancer, where HER2 overexpression or amplification correlates with aggressive tumor behavior and po...

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Literature Corpus work
98bade9f-78c7-5183-b52d-7fc5c5663137
DOI
10.20944/preprints202406.0515.v1
Open publication

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