TLR7 Polymorphism (rs179008 and rs179009) in HIV-Infected Individual Naïve to ART.

doi:10.1155/2020/6702169

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Article

TLR7 Polymorphism (rs179008 and rs179009) in HIV-Infected Individual Naïve to ART.

Mediators of inflammation - 1 Jan 2020

Singh HariOm, Samani Dharmesh, Aggarwal Sumit

Abstract excerpt

Toll-like receptors (TLRs) play an important role in the innate immune response to HIV infection. Single nucleotide polymorphism (SNP) in TLR7 (Gln11Leu) gene has been associated with a rapid decline of CD4T cell count. Hence, we assessed the TLR7 (rs179008, Gln11Leu (A/T) and rs179009, IVS2-151 (A/G)) polymorphism in 150 HIV-infected individuals naïve to ART and 158 healthy controls. The genotyping of TLR7...

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PMID: 32565728
DOI: 10.1155/2020/6702169
PMCID: PMC7256714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.