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Article

The role of mitochondrial DNA copy number in autoimmune disease: a bidirectional two sample mendelian randomization study.

Frontiers in immunology - 1 Jan 2024

Liu Zhekang, Fu Qingan, Shao Yijia, Duan Xinwang

Abstract excerpt

Background: Mitochondrial DNA (mtDNA) plays an important role in autoimmune diseases (AD), yet the relationship between mitochondria and autoimmune disease is controversial. This study employed bidirectional Mendelian randomization (MR) to explore the causal relationship between mtDNA copy number and 13 ADs (including ankylosing spondylitis [AS], Crohn's disease [CD], juvenile rheumatoid arthritis [JRA],...

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Share to Autoimmune Diseases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 39464879
DOI: 10.3389/fimmu.2024.1409969
PMCID: PMC11502960

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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