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Article

Alteration of telomere length and mtDNA copy number in interstitial lung disease associated with rheumatoid arthritis

4 Mar 2025

Abstract excerpt

Interstitial lung disease (ILD) is a common extra-articular manifestation of rheumatoid arthritis (RA). The inflammatory response in lung disease is characterized by severe oxidative stress, which enhances cellular senescence. Telomeric shortening and mitochondria dysregulation represent two hallmarks of cellular senescence. The maintenance of telomere length (TL) and mitochondrial DNA (mtDNA) copy number is...

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Share to Extracellular vesicles in disease
Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40035723
DOI: 10.1080/08916934.2025.2473741

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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