Article
Extent and prognostic value of MGMT promotor methylation in glioma WHO grade II.
Scientific reports - 12 Nov 2020
Karschnia Philipp, Teske Nico, Dorostkar Mario M, Siller Sebastian, Weller Jonathan, Baehring Joachim M, Dietrich Jorg, von Baumgarten Louisa, Herms Jochen, Tonn Joerg-Christian, Thon Niklas
Abstract excerpt
MGMT promotor methylation is associated with favourable outcome in high-grade glioma. In glioma WHO grade II, it is unclear whether the extent of MGMT promotor methylation and its prognostic role is independent from other molecular markers. We performed a retrospective analysis of 155 patients with glioma WHO grade II. First, all 155 patients were assigned to three molecular groups according to the 2016 WHO...
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