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The role of clinical and molecular factors in low-grade gliomas: what is their impact on survival?

Future oncology (London, England) - 1 Jul 2018

Franceschi Enrico, Mura Antonella, De Biase Dario, Tallini Giovanni, Pession Annalisa, Foschini Maria Pia, Danieli Daniela, Pizzolitto Stefano, Zunarelli Elena, Lanza Giovanni, Bartolini Daniela, Silini Enrico Maria, Visani Michela, Di Oto Enrico, Tosoni Alicia, Minichillo Santino, Lamberti Giuseppe, Lanese Andrea, Paccapelo Alexandro, Bartolini Stefania, Brandes Alba A

Abstract excerpt

AIM: To evaluate relevance of clinical and molecular factors in adult low-grade gliomas (LGG) and to correlate with survival. METHODS: We reviewed records from adult LGG patients from 1991 to 2015 who received surgery and had sufficient tissue to molecular biomarkers characterization. RESULTS: 213 consecutive LGG patients were included: 17.4% were low-risk, according to Radiation Therapy Oncology Group (RTOG)...

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Chromosome Deletion
Chromosomes, Human, Pair 1
DNA Modification Methylases
DNA Repair Enzymes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Isocitrate Dehydrogenase

Multivariate Analysis

Neurosurgical Procedures

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PMID: 29938525
DOI: 10.2217/fon-2017-0634

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MGMT

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