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Article

Systematic Assessment of Antiviral Potency, Breadth, and Synergy of Triple Broadly Neutralizing Antibody Combinations against Simian-Human Immunodeficiency Viruses.

Journal of virology - 13 Jan 2021

Berendam Stella J, Styles Tiffany M, Morgan-Asiedu Papa K, Tenney DeAnna, Kumar Amit, Obregon-Perko Veronica, Bar Katharine J, Saunders Kevin O, Santra Sampa, De Paris Kristina, Tomaras Georgia D, Chahroudi Ann, Permar Sallie R, Amara Rama R, Fouda Genevieve G

Abstract excerpt

Daily burden and clinical toxicities associated with antiretroviral therapy (ART) emphasize the need for alternative strategies to induce long-term human immunodeficiency virus (HIV) remission upon ART cessation. Broadly neutralizing antibodies (bNAbs) can both neutralize free virions and mediate effector functions against infected cells and therefore represent a leading immunotherapeutic approach. To increase...

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Topics

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Share to Antibodies, Monoclonal
Share to Antibody-Dependent Cell Cytotoxicity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Broadly Neutralizing Antibodies

Share to env Gene Products, Human Immunodeficiency Virus

Share to HIV Antibodies

Share to Immunization, Passive

Share to Simian Acquired Immunodeficiency Syndrome

Share to Simian Immunodeficiency Virus

Source

Open in PubMed Open full text

Identifiers

PMID: 33177194
DOI: 10.1128/JVI.01667-20
PMCID: PMC7925105

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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