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Nasal DNA methylation differentiates severe from non‐severe asthma in African‐American children

11 Nov 2020

Abstract excerpt

BACKGROUND: Asthma is highly heterogeneous, and severity evaluation is key to asthma management. DNA methylation (DNAm) contributes to asthma pathogenesis. This study aimed to identify nasal epithelial DNAm differences between severe and nonsevere asthmatic children and evaluate the impact of environmental exposures. METHODS: Thirty-three nonsevere and 22 severe asthmatic African American children were included...

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PMID: 33175399
DOI: 10.1111/all.14655

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