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Article

Significance of tumor mutation burden combined with immune infiltrates in the progression and prognosis of ovarian cancer

5 Aug 2020

Abstract excerpt

BACKGROUND: Ovarian cancer (OC) is the most malignant tumor in the female reproductive system. About 75% of OC in complete remission of clinical symptoms still develop a recurrence. Therefore, searching for new treatment methods plays an important role in improving the prognosis of OC. METHODS: We downloaded the MAF files, RNA-seq data and clinical information from the TCGA database. The "maftools" package in R...

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PMID: 32774167
DOI: 10.1186/s12935-020-01472-9

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