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Article

Multiomics analysis of tumor mutational burden across cancer types

1 Jan 2021

Abstract excerpt

Whether tumor mutational burden (TMB) is related to improved survival outcomes or the promotion of immunotherapy in various malignant tumors remains controversial, and we lack a comprehensive understanding of TMB across cancers. Based on the data obtained from The Cancer Genome Atlas (TCGA), we conducted a multiomics analysis of TMB across 21 cancer types to identify characteristics related to TMB and determine...

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Cancer Immunotherapy and Biomarkers
Epigenetics and DNA Methylation
Ferroptosis and cancer prognosis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34745455
DOI: 10.1016/j.csbj.2021.10.013

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