Article
The prognostic value of tumor mutation burden (TMB) and its relationship with immune infiltration in breast cancer patients.
European journal of medical research - 20 Feb 2023
Cui Shengjin, Feng Jingying, Tang Xi, Lou Shuang, Guo Weiquan, Xiao Xiaowei, Li Shuping, Chen Xue, Huan Yu, Zhou Yiwen, Xiao Lijia
Abstract excerpt
OBJECTIVE: Although the tumor mutation burden (TMB) was reported as a biomarker for immunotherapy of various cancers, whether it can effectively predict the survival prognosis in breast cancer patients remains unclear. In this study, the prognostic value of TMB and its correlation with immune infiltration were explored by using multigroup studies. METHODS: The somatic mutation data of 986 breast cancer patients...
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