Article
Association between tumor mutation burden and immune infiltration in ovarian cancer.
International immunopharmacology - 1 Dec 2020
Fan Suzhen, Gao Xiang, Qin Qiaohong, Li Hongyu, Yuan Zhongfu, Zhao Shujun
Abstract excerpt
BACKGROUND: It remains unclear whether the tumor mutation burden (TMB) or a TMB-related signature could be prognostic indicators in ovarian cancer (OC), as potential correlations with immune infiltrates and immunotherapy responsiveness remains poorly understood. METHODS: Data of 941 OC patients were collected from three datasets, including 587, 260, and 94 patients from The Cancer Genome Atlas (TCGA), GSE32062,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
