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Article

Novel score test to increase power in association test by integrating external controls.

Genetic epidemiology - 1 Apr 2021

Li Yatong, Lee Seunggeun

Abstract excerpt

Recent advances in genotyping and sequencing technologies have enabled genetic association studies to leverage high-quality genotyped data to identify variants accounting for a substantial portion of disease risk. The usage of external controls, whose genomes have already been genotyped and are publicly available, could be a cost-effective approach to increase the power of association testing. There has been...

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PMID: 33161601
DOI: 10.1002/gepi.22370
PMCID: PMC9424128

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