Article
An exposure-weighted score test for genetic associations integrating environmental risk factors.
Biometrics - 1 Sept 2015
Han Summer S, Rosenberg Philip S, Ghosh Arpita, Landi Maria Teresa, Caporaso Neil E, Chatterjee Nilanjan
Abstract excerpt
Current methods for detecting genetic associations lack full consideration of the background effects of environmental exposures. Recently proposed methods to account for environmental exposures have focused on logistic regressions with gene-environment interactions. In this report, we developed a test for genetic association, encompassing a broad range of risk models, including linear, logistic and probit, for...
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