Article
Identifying genetic marker sets associated with phenotypes via an efficient adaptive score test.
Biostatistics (Oxford, England) - 1 Sept 2012
Cai Tianxi, Lin Xihong, Carroll Raymond J
Abstract excerpt
In recent years, genome-wide association studies (GWAS) and gene-expression profiling have generated a large number of valuable datasets for assessing how genetic variations are related to disease outcomes. With such datasets, it is often of interest to assess the overall effect of a set of genetic markers, assembled based on biological knowledge. Genetic marker-set analyses have been advocated as more reliable...
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