Article
Revisiting the role of factor H in age-related macular degeneration: Insights from complement-mediated renal disease and rare genetic variants.
Survey of ophthalmology - 1 Jan 2000
Tzoumas Nikolaos, Hallam Dean, Harris Claire L, Lako Majlinda, Kavanagh David, Steel David H W
Abstract excerpt
Ophthalmologists are long familiar with the eye showing signs of systemic disease, but the association between age-related macular degeneration and abnormal complement activation, common to several renal disorders, has only recently been elucidated. Although complement activation products were identified in drusen almost three decades ago, it was not until the early 21st century that a single-nucleotide...
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