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Article

Genetic deficiency of complement factor H in a patient with age-related macular degeneration and membranoproliferative glomerulonephritis.

Molecular immunology - 1 May 2008

Montes Tamara, Goicoechea de Jorge Elena, Ramos Rosa, Gomà Montserrat, Pujol Octavi, Sánchez-Corral Pilar, Rodríguez de Córdoba Santiago

Abstract excerpt

Age-related macular degeneration (AMD) and membranoproliferative glomerulonephritis type II (MPGN2) are dense deposit diseases that share a genetic association with complement genes and have complement proteins as important components of the dense deposits. Here, we present the case of a 64-year-old smoker male who developed both AMD and MPGN2 in his late 50s. The patient presented persistent low plasma levels of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18336910
DOI: 10.1016/j.molimm.2008.01.027

Genes

CFH
CFB
CFHR1
CFHR3
HTRA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Genetic deficiency of complement factor H in a patient with age-related macular degeneration and membranoproliferative glomerulonephritis.PMID 18336910Read ↗

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