Article
Genetic Correlation Analysis and Transcriptome-wide Association Study Suggest the Overlapped Genetic Mechanism between Gout and Attention-deficit Hyperactivity Disorder.
Canadian journal of psychiatry. Revue canadienne de psychiatrie - 1 Dec 2021
Kafle Om Prakash, Wang Xi, Cheng Shiqiang, Ding Miao, Li Ping, Cheng Bolun, Liang Xiao, Liu Li, Du Yanan, Ma Mei, Zhang Lu, Zhao Yan, Wen Yan, Zhang Feng
Abstract excerpt
OBJECTIVES: Gout is a common inflammatory arthritis, which is caused by hyperuricemia. Limited efforts have been paid to systematically explore the relationships between gout and common psychiatric disorders. METHODS: Genome-wide association study summary data of gout were obtained from the GeneATLAS, which contained 452,264 participants including 3,528 gout cases. Linkage disequilibrium score regression (LDSC)...
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