Article
Histone H3K27M Mutation in Brain Tumors.
Advances in experimental medicine and biology - 1 Jan 2021
El-Hashash Ahmed H K
Abstract excerpt
Histones form chromatin and play a key role in the regulation of gene expression. As an epigenetic information form, histone modifications such as methylation, phosphorylation, acetylation, and ubiquitination are closely related to the regulation of genes. In the last two decades, cancer scientists discovered that some histone modifications, including acetylation and methylation, are perturbed in cancer diseases....
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