Article
Assessing the role of SH3RF1 and SH3RF2 polymorphisms in susceptibility to tuberculosis: A case-control study in the Han Chinese population.
Microbial pathogenesis - 1 Mar 2021
Chen Hao, Zhou Juan, Jiao Lin, Song Jiajia, Zhong Huiyu, Zhao Zhenzhen, Meng Zirui, Lu Xiaojun, Chen Xuerong, Zhang Wei, Ying Binwu
Abstract excerpt
BACKGROUND: Tuberculosis (TB) remains a major public health problem. SH3RF1 and SH3RF2 are candidate genes with multiple single-nucleotide polymorphisms (SNPs) that have the potential to participate in Mycobacterium infection via activation of the JNK signaling pathway. In this case-control study, we aimed to investigate the association of five SH3RF1 and SH3RF2 SNPs with susceptibility to TB in the Western...
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