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Article

Tagging single nucleotide polymorphisms in the IRF1 and IRF8 genes and tuberculosis susceptibility.

PloS one - 1 Jan 2012

Ding Shiping, Jiang Tao, He Jianqin, Qin Beibei, Lin Shuangyan, Li Lanjuan

Abstract excerpt

Genes encoding IRF1 and IRF8 protein have been proposed as candidate tuberculosis susceptibility genes. In order to elucidate whether the IRF1 and IRF8 variants were associated with tuberculosis susceptibility, we conducted a case-control study consisting of 495 controls and 452 ethnically matched cases with tuberculosis in a Chinese population. Seven haplotype tagging single-nucleotide polymorphisms (tagSNPs)...

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Identifiers

PMID: 22879909
DOI: 10.1371/journal.pone.0042104
PMCID: PMC3412841

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