Article
Clinical Implications of Pre- and Postoperative Circulating Tumor DNA in Patients with Resected Pancreatic Ductal Adenocarcinoma.
Annals of surgical oncology - 1 Jun 2021
Yamaguchi Takuro, Uemura Kenichiro, Murakami Yoshiaki, Kondo Naru, Nakagawa Naoya, Okada Kenjiro, Seo Shingo, Hiyama Eiso, Takahashi Shinya, Sueda Taijiro
Abstract excerpt
BACKGROUND: The clinical implications of pre- and postoperative KRAS-mutated circulating tumor DNA (ctDNA) present in patients with pancreatic ductal adenocarcinoma (PDAC) have remained an unresolved issue. This study sought to investigate the clinical significance of pre- and postoperative ctDNA analyses and their impact on the prognosis of PDAC patients. METHODS: Digital droplet polymerase chain reaction...
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