Article
Prognostic value of circulating tumour DNA in patients undergoing curative resection for pancreatic cancer.
British journal of cancer - 28 Jun 2016
Hadano Naoto, Murakami Yoshiaki, Uemura Kenichiro, Hashimoto Yasusi, Kondo Naru, Nakagawa Naoya, Sueda Taijiro, Hiyama Eiso
Abstract excerpt
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is frequently diagnosed at an advanced stage, leading to a poor prognosis. Therefore, interest in the development of non-invasive biomarkers for prognostic prediction has grown rapidly. Here, we assessed the clinical implications of v-Ki-ras2 kirsten rat sarcoma viral oncogene homolog (KRAS)-mutated circulating tumour DNA (ctDNA) as a useful surrogate biomarker...
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