Article
Plasma KRAS mutations predict the early recurrence after surgical resection of pancreatic cancer.
Cancer biology & therapy - 2 Dec 2021
Ako Soichiro, Kato Hironari, Nouso Kazuhiro, Kinugasa Hideaki, Terasawa Hiroyuki, Matushita Hiroshi, Takada Saimon, Saragai Yosuke, Mizukawa Sho, Muro Shinichiro, Uchida Daisuke, Tomoda Takeshi, Matsumoto Kazuyuki, Horiguchi Shigeru, Nobuoka Daisuke, Yoshida Ryuichi, Umeda Yuzo, Yagi Takahito, Okada Hiroyuki
Abstract excerpt
BACKGROUND: The technique to analyze circulating tumor DNA (ctDNA) in body fluid (so-called "liquid biopsy") is recently developed. AIMS: Our aim was to assess the utility of liquid biopsy for predicting progression of pancreatic ductal adenocarcinoma (PDAC) after surgical resection or chemotherapy. METHODS: A total of 72 patients with PDAC were retrospectively enrolled for this study, 33 treated surgically and...
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