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Article

Clinical implication of oncogenic somatic mutations in early-stage cervical cancer with radical hysterectomy.

Scientific reports - 30 Oct 2020

Watanabe Takafumi, Nanamiya Hideaki, Kojima Manabu, Nomura Shinji, Furukawa Shigenori, Soeda Shu, Tanaka Daisuke, Isogai Takao, Imai Jun-Ichi, Watanabe Shinya, Fujimori Keiya

Abstract excerpt

It is well known that tumour initiation and progression are primarily an accumulation of genetic mutations. The mutation status of a tumour may predict prognosis and enable better selection of targeted therapies. In the current study, we analysed a total of 55 surgical tumours from stage IB-IIB cervical cancer (CC) patients who had undergone radical hysterectomy including pelvic lymphadenectomy, using a cancer...

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Identifiers

PMID: 33127935
DOI: 10.1038/s41598-020-72518-1
PMCID: PMC7599240

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