Prevalence and Prognostic Significance of PIK3CA Mutation and CNV Status and Phosphorylated AKT Expression in Patients With Cervical Cancer Treated With Primary Surgery.

doi:10.1097/PGP.0000000000000978

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Prevalence and Prognostic Significance of PIK3CA Mutation and CNV Status and Phosphorylated AKT Expression in Patients With Cervical Cancer Treated With Primary Surgery.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Mar 2024

Martell Kevin, McIntyre John B, Abedin Tasnima, Kornaga Elizabeth N, Chan Angela M Y, Enwere Emeka, Köbel Martin, Dean Michelle L, Phan Tien, Ghatage Prafull, Lees-Miller Susan P, Doll Corinne M

Abstract excerpt

Currently, there are limited and conflicting reports on the prognostic utility of PIK3CA and associated pathway markers for cervical cancers treated with primary surgical management. Moreover, current studies are lacking complete characterization of adjuvant treatment with RT and/or chemotherapy. We aimed to document the prevalence, clinicopathologic, adjuvant treatment details, and prognostic value of PI3K/AKT...

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PMID: 37668363
DOI: 10.1097/PGP.0000000000000978

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Prevalence and Prognostic Significance of PIK3CA Mutation and CNV Status and Phosphorylated AKT Expression in Patients With Cervical Cancer Treated With Primary Surgery.PMID 37668363Read ↗

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