Article
An osmotically induced cytosolic Ca2+ transient activates calcineurin signaling to mediate ion homeostasis and salt tolerance of Saccharomyces cerevisiae.
The Journal of biological chemistry - 6 Sept 2002
Matsumoto Tracie K, Ellsmore Amanda J, Cessna Stephen G, Low Philip S, Pardo José M, Bressan Ray A, Hasegawa Paul M
Abstract excerpt
Hyperosmotic stress caused by NaCl, LiCl, or sorbitol induces an immediate and short duration ( approximately 1 min) transient cytosolic Ca(2+) ([Ca(2+)](cyt)) increase (Ca(2+)-dependent aequorin luminescence) in Saccharomyces cerevisiae cells. The amplitude of the osmotically induced [Ca(2+)](cyt) transient was attenuated by the addition of chelating agents EGTA or BAPTA, cation channel pore blockers,...
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