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Article

Trimethylamine N-oxide and the reverse cholesterol transport in cardiovascular disease: a cross-sectional study.

Scientific reports - 29 Oct 2020

Bordoni Laura, Samulak Joanna J, Sawicka Angelika K, Pelikant-Malecka Iwona, Radulska Adrianna, Lewicki Lukasz, Kalinowski Leszek, Gabbianelli Rosita, Olek Robert A

Abstract excerpt

The early atherosclerotic lesions develop by the accumulation of arterial foam cells derived mainly from cholesterol-loaded macrophages. Therefore, cholesterol and cholesteryl ester transfer protein (CETP) have been considered as causative in atherosclerosis. Moreover, recent studies indicate the role of trimethylamine N-oxide (TMAO) in development of cardiovascular disease (CVD). The current study aimed to...

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Source

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Identifiers

PMID: 33122777
DOI: 10.1038/s41598-020-75633-1
PMCID: PMC7596051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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