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Article

Homocysteine and methylenetetrahydrofolate reductase C677T and A1298C polymorphisms in Tunisian patients with severe coronary artery disease.

Journal of thrombosis and thrombolysis - 1 Feb 2009

Ghazouani Lakhdar, Abboud Nesrine, Mtiraoui Nabil, Zammiti Walid, Addad Faouzi, Amin Haitham, Almawi Wassim Y, Mahjoub Touhami

Abstract excerpt

Elevation in homocysteine and methylenetetrahydrofolate reductase (MTHFR) gene variants, C677T and A1298C, have been linked with atherothrombosis. However their exact contribution to coronary artery disease (CAD) remains controversial. Moreover, data from Tunisian patients are scarse. We examined the association of MTHFR C677T and A1298C, and changes in plasma homocysteine in 352 Tunisian patients with...

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Source

Identifiers

PMID: 18204887
DOI: 10.1007/s11239-008-0194-1

Genes

CAD
MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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