Article
Exome-wide association study of replicable nonsynonymous variants conferring risk for alcohol dependence.
Journal of studies on alcohol and drugs - 1 Jul 2013
Zuo Lingjun, Saba Laura, Wang Kesheng, Zhang Xiangyang, Krystal John H, Tabakoff Boris, Luo Xingguang
Abstract excerpt
OBJECTIVE: In the present study, we scanned the whole exome in three independent samples to search for replicable risk nonsynonymous (ns) variants (ns single-nucleotide polymorphisms [nsSNPs]) for alcohol dependence. METHOD: A total of 10,554 subjects in three independent samples were analyzed for association with alcohol dependence, including one European American sample (1,409 cases with alcohol dependence and...
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