Article
Evaluation of the Association between Programmed Cell Death-1 Gene Polymorphisms and Hepatocellular Carcinoma Susceptibility in Turkish Subjects. A Pilot Study.
Journal of gastrointestinal and liver diseases : JGLD - 27 Oct 2020
Demirci Abdullah Fatih, Demirtas Coskun Ozer, Eren Fatih, Yilmaz Demet, Keklikkiran Caglayan, Ozdogan Osman Cavit, Gunduz Feyza
Abstract excerpt
BACKGROUND AND AIMS: Programmed cell death-1 (PD-1) has a vital role in regulating T-cell function, and immune escape mechanism of cancer cells. It was shown that there could be a relationship between single nucleotide polymorphisms (SNPs) in the PD-1 gene and susceptibility to hepatocellular carcinoma (HCC) based on various studies. We aimed to investigate the role of three SNPs within the PD-1 gene in...
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