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Article

Temporal-specific roles of Rac1 during vascular development and retinal angiogenesis.

Developmental biology - 15 Mar 2016

Nohata Nijiro, Uchida Yutaka, Stratman Amber N, Adams Ralf H, Zheng Yi, Weinstein Brant M, Mukouyama Yoh-Suke, Gutkind J Silvio

Abstract excerpt

Angiogenesis, the formation of new blood vessels by remodeling and growth of pre-existing vessels, is a highly orchestrated process that requires a tight balance between pro-angiogenic and anti-angiogenic factors and the integration of their corresponding signaling networks. The family of Rho GTPases, including RhoA, Rac1, and Cdc42, play a central role in many cell biological processes that involve cytoskeletal...

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Share to Endothelial Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Human Umbilical Vein Endothelial Cells

Share to Neovascularization, Physiologic

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Share to rac1 GTP-Binding Protein

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Source

Identifiers

PMID: 26872874
DOI: 10.1016/j.ydbio.2016.02.005

Genes

RAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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