Article
Sequencing of Sclerosing Microcystic Adenocarcinoma Identifies Mutational Burden and Somatic Variants Associated With Tumorigenesis.
Anticancer research - 1 Nov 2020
Jiang Roy, Marquez Jonathan, Tower Jacob I, Jacobs Daniel, Chen Wenqian, Mehra Saral, Prasad Manju Lata, Judson Benjamin L
Abstract excerpt
BACKGROUND/AIM: Sclerosing microcystic adenocarcinoma (SMA) is a rare oral cavity neoplasia, histologically resembling microcystic adnexal carcinoma (MAC) of the skin. Only nine SMA cases have been reported in the literature, frequently in the context of immunosuppression; SMA has not been recognized in the most recent WHO tumor classification. We sought to identify potential molecular mechanisms of tumorigenesis...
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