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Evidence Supporting That C-to-U RNA Editing Is the Major Force That Drives SARS-CoV-2 Evolution.

Journal of molecular evolution - 1 Apr 2023

Wang Jinxiang, Wu Liqun, Pu Xiaoxin, Liu Baoyi, Cao Meiling

Abstract excerpt

Mutations of DNA organisms are introduced by replication errors. However, SARS-CoV-2, as an RNA virus, is additionally subjected to rampant RNA editing by hosts. Both resources contributed to SARS-CoV-2 mutation and evolution, but the relative prevalence of the two origins is unknown. We performed comparative genomic analyses at intra-species (world-wide SARS-CoV-2 strains) and inter-species (SARS-CoV-2 and...

Topics

Humans
SARS-CoV-2
COVID-19
RNA Editing
Genome, Viral
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36799984
DOI: 10.1007/s00239-023-10097-1
PMCID: PMC9936484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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