Pro-inflammatory cytokine response pre-dominates immuno-genetic pathway in development of rheumatoid arthritis.

Abstract excerpt

Rheumatoid arthritis (RA) is a crucial inflammatory joint disease characterized by loss of self-tolerance and severe cartilage loss, autoimmune, and subchondral bone erosions. Cytokines are the key regulators of inflammatory responses. Homeostatic imbalances in pro- and anti-inflammatory cytokine activities can result in pathogenic inflammatory reactions. These imbalances could be initiated by environmental...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Arthritis, Rheumatoid
• Share to Case-Control Studies