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Article

TGF-β1 +869C/T polymorphism increases susceptibility to rheumatoid arthritis in North Indian population.

Clinical rheumatology - 1 Oct 2020

Patel Sipahee Lal, Prakash Jaya, Gupta Varsha

Abstract excerpt

OBJECTIVES: Rheumatoid arthritis (RA) is a heterogeneous autoimmune disease, characterized by chronic inflammation, hyperplasia (swelling), tenderness, erosion of cartilage and bones in synovial joints. Transforming growth factor-β1 (TGF-β1) is an important regulator of inflammation, and its polymorphism is implicated in several diseases. Therefore, the study was done to determine whether TGF-β1 C/T gene...

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PMID: 32270333
DOI: 10.1007/s10067-020-05064-w

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