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Article

Proinflammatory Cytokines (IL-1, -6, -8, -15, -17, -18, -23, TNF-α) Single Nucleotide Polymorphisms in Rheumatoid Arthritis-A Literature Review.

International journal of molecular sciences - 14 Feb 2022

Koper-Lenkiewicz Olga M, Sutkowska Kinga, Wawrusiewicz-Kurylonek Natalia, Kowalewska Ewa, Matowicka-Karna Joanna

Abstract excerpt

Conducted studies highlight that a mixture of genetic and environmental factors is responsible for rheumatoid arthritis (RA) development. This study aimed to analyze the available literature for the relationship between, on the one hand, single-nucleotide polymorphisms (SNPs) in the proinflammatory cytokines genes interleukin-1 (IL-1), -6, -8, -15, -17, -18, and -23, and tumor necrosis factor-alpha (TNF-α), and...

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Share to Arthritis, Rheumatoid
Share to Cytokine Signaling Pathways and Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

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Share to Polymorphism, Single Nucleotide

Share to Rheumatoid Arthritis Research and Therapies

Share to Systemic Lupus Erythematosus Research

Source

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Identifiers

PMID: 35216226
DOI: 10.3390/ijms23042106
PMCID: PMC8878005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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