Relationship Between Genetic Risk and Age of Diagnosis in Systemic Lupus Erythematosus.

doi:10.3899/jrheum.200002

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Article

Relationship Between Genetic Risk and Age of Diagnosis in Systemic Lupus Erythematosus.

The Journal of rheumatology - 1 Jun 2021

Dominguez Daniela, Kamphuis Sylvia, Beyene Joseph, Wither Joan, Harley John B, Blanco Irene, Vila-Inda Catarina, Brunner Hermine, Klein-Gitleman Marissa, McCurdy Deborah, Wahezi Dawn M, Lehman Thomas, Jelusic Marija, Peschken Christine A, Pope Janet E, Gladman Dafna D, Hanly John G, Clarke Ann E, Bernatsky Sasha, Pineau Christian, Smith C Douglas, Barr Susan, Boire Gilles, Rich Eric, Silverman Earl D

Abstract excerpt

OBJECTIVE: Specific risk alleles for childhood-onset systemic lupus erythematosus SLE (cSLE) vs adult-onset SLE (aSLE) patients have not been identified. The aims of this study were to determine if there is an association (1) between non-HLA-related genetic risk score (GRS) and age of SLE diagnosis, and (2) between HLA-related GRS and age of SLE diagnosis. METHODS: Genomic DNA was obtained from 2001 multiethnic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33060314
DOI: 10.3899/jrheum.200002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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