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Article

Genetic variants in systemic lupus erythematosus susceptibility loci, XKR6 and GLT1D1 are associated with childhood-onset SLE in a Korean cohort.

Scientific reports - 2 Jul 2018

Joo Young Bin, Lim Jiwoo, Tsao Betty P, Nath Swapan K, Kim Kwangwoo, Bae Sang-Cheol

Abstract excerpt

Impact of genetic variants on the age of systemic lupus erythematosus (SLE) onset was not fully understood. We investigated a cumulative effect of SLE-risk variants on the age of SLE onset and scanned genome-wide SNPs to search for new risk loci of childhood-onset SLE (cSLE). We analyzed 781 Korean single-center SLE subjects who previously genotyped by both Immunochip and genome-wide SNP arrays. Individual...

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Identifiers

PMID: 29967481
DOI: 10.1038/s41598-018-28128-z
PMCID: PMC6028392

Genes

XKR6

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