Article
Familial Aggregation of Childhood- and Adulthood-Onset Systemic Lupus Erythematosus.
Arthritis care & research - 1 Aug 2020
Sinicato Nailú Angélica, de Oliveira Luciana, Lapa AlineTamires, Postal Mariana, Peliçari Karinade Oliveira, Costallat Lilian T L, Marini Roberto, Gil-da-Silva-Lopes Vera Lúcia, Niewold Timothy B, Appenzeller Simone
Abstract excerpt
OBJECTIVE: To assess the familial occurrence of systemic lupus erythematosus (SLE) in a large Brazilian cohort. METHODS: Consecutive patients with SLE were recruited and stratified according to age at disease onset into childhood-onset SLE or adult-onset SLE. Each patient was personally interviewed regarding the history of SLE across 3 generations (first-, second-, and third-degree relatives). Recurrence rates...
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